Buenos Dias...even though I don't speak Spanish...it actually comes fairly easily as Mexicans speak more closely actual Spanish. And so day 3, I only have the morning here and must also present my poster.
The first session related new material on the viral evolution in acute disease (AHI).Fro this we gleaned the relationships between the linkage and characterization of transmitted virus during acute infection. We then continued the discussion to transmission of HIV-1 Gag but not Nef immune escape mechanisms as associated with reduced viral loads in those with HIV infection, and the relationship and differences between those identified resistance mutations in acute and latent viral infections. This session finished off with a hearty discussion about relatoin of viral fitness and HIV transmission and features of HIV-1 subtype C virus and the idea of compartmentalism in male secretions as increasing the virulence of the virus transmission.
Interestingly we also had a chance to review all the findings on the modified CD38 peptide inhibiting HIV attachment through the involvement of a lysine (K57) residue and its' potential as an active microbicide based on the above discussion of increased male viral virulence in semen.
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